Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586459 | 0.83 | ALDH1A1 (0.49) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL21622730 | 0.83 | NPC1 (0.50) | PKMGAAKDM4EALDH1A1GLA | |
| SCHEMBL21622747 | 0.70 | KDM4E (0.56) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917174 | 0.70 | KDM4E (0.49) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6639327 | 0.68 | ALDH1A1 (0.46) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL304891 | 0.68 | CXCR2 (0.54) | PKMGAAKDM4EALDH1A1HPGD | |
| SCHEMBL2218369 | 0.67 | MAPT (0.46) | PKMGAAKDM4EALDH1A1GLA | |
| SCHEMBL16966432 | 0.67 | PIM1 (0.47) | PKMGAAKDM4EALDH1A1GLA | |
| SCHEMBL1920752 | 0.66 | CXCR2 (0.52) | PKMGAAKDM4EALDH1A1HPGD | |
| SCHEMBL29587927 | 0.65 | MEN1 (0.53) | GAAKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820966-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-08 | — | — | EP | disclosed |