Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | GLA | P06280 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489595 | 0.83 | PKM (0.44) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL21622747 | 0.79 | KDM4E (0.56) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL23917174 | 0.79 | KDM4E (0.49) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL6639327 | 0.76 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL23294864 | 0.75 | TSHR (0.40) | ALDH1A1GAAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL2163345 | 0.73 | USP7 (0.50) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL29587927 | 0.72 | MEN1 (0.53) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL24489622 | 0.71 | KDM4E (0.47) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL839837 | 0.71 | ALDH1A1 (0.62) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL21622730 | 0.70 | NPC1 (0.50) | ALDH1A1GAAKDM4EGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312717-B | Substituted fused heteroaromatic tricyclic compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2022-04-12 | — | — | CN | disclosed |