SCHEMBL24490481

SCHEMBL24490481

CCCCCC/C(=N\OC(C)=O)C(=O)c1ccc2c(c1)C(CCCC)(CCCC)c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 12/20 0.36
▸ APEX1 P27695 1/20 0.36
▸ CYP2C19 P33261 1/20 0.35
▸ CES2 O00748 2/20 0.34
▸ CES1 P23141 2/20 0.34
▸ PTGS2 P35354 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ PTPN11 Q06124 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24490485 0.96 PDK2 (0.36) PDK2APEX1CES2CES1PTGS2
SCHEMBL24490462 0.96 PDK2 (0.36) PDK2APEX1CES2CES1PTGS2
SCHEMBL24490482 0.93 PDK2 (0.36) PDK2APEX1CYP2C19CES2CES1
SCHEMBL24490484 0.88 PDK2 (0.37) PDK2CES2CES1PTGS2PTPN11
SCHEMBL13538673 0.88 PDK2 (0.38) PDK2APEX1PTPN11
SCHEMBL25119573 0.87 PDK2 (0.35) PDK2APEX1CYP2C19CES2CES1
SCHEMBL26818789 0.87 PDK2 (0.39) PDK2APEX1CYP2C19
SCHEMBL18235853 0.87 PDK2 (0.39) PDK2APEX1CYP2C19
SCHEMBL24490441 0.86 PDK2 (0.35) PDK2APEX1CYP2C19
SCHEMBL21431271 0.86 RXRA (0.33) CES2CES1PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239922-A1 PHOTOCURABLE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-18 — — US disclosed
US-20240239922-A1 PHOTOCURABLE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-18 — — US disclosed
US-20230242692-A1 COMPOSITION AND CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2023-08-03 — — US disclosed
US-20230242692-A1 COMPOSITION AND CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2023-08-03 — — US disclosed
WO-2023127402-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING PATTERNED CURED FILM 東京応化工業株式会社 2023-07-06 — — WO disclosed
WO-2023127401-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING PATTERNED CURED FILM 東京応化工業株式会社 2023-07-06 — — WO disclosed
WO-2023120077-A1 COMPOSITION, AND PHOTOSENSITIVE COMPOSITION 東京応化工業株式会社 2023-06-29 — — WO disclosed
WO-2023120076-A1 PHOTOSENSITIVE COMPOSITION 東京応化工業株式会社 2023-06-29 — — WO disclosed
WO-2023074265-A1 PHOTOSENSITIVE COMPOSITION 東京応化工業株式会社 2023-05-04 — — WO disclosed
WO-2023074264-A1 PHOTOSENSITIVE COMPOSITION 東京応化工業株式会社 2023-05-04 — — WO disclosed
WO-2023047855-A1 COMPOSITION AND PHOTOSENSITIVE COMPOSITION 東京応化工業株式会社 2023-03-30 — — WO disclosed
WO-2023047856-A1 COMPOSITION AND PHOTOSENSITIVE COMPOSITION 東京応化工業株式会社 2023-03-30 — — WO disclosed
US-20230002520-A1 CURABLE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-05 — — US disclosed
WO-2022181562-A1 PHOTOCURABLE LIQUID COMPOSITION, CURED OBJECT, AND METHOD FOR PRODUCING CURED OBJECT 東京応化工業株式会社 2022-09-01 — — WO disclosed
US-20220177641-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2022-06-09 — — US disclosed
US-20220177673-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2022-06-09 — — US disclosed
US-20220177625-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2022-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177625-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND CROCC, RCSD1, CRYZ PDK2 4077/4885APEX1 3904/4885CYP2C19 1679/4885
US-20220177641-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND CROCC, RCSD1, WDR5 PDK2 4363/4885APEX1 3423/4885CYP2C19 2178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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