Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.34 |
| ▸ | LPL | P06858 | 4/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980791 | 0.83 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL1908293 | 0.82 | LIPG (0.35) | LIPGLPLF2F11PRSS1 | |
| SCHEMBL1908290 | 0.82 | LIPG (0.35) | LIPGLPLF2F11PRSS1 | |
| SCHEMBL18813762 | 0.79 | LIPG (0.35) | LIPGLPLDGAT1HCRTR1HCRTR2 | |
| SCHEMBL18813763 | 0.79 | LIPG (0.35) | LIPGLPLDGAT1HCRTR1HCRTR2 | |
| SCHEMBL16005083 | 0.78 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL934131 | 0.78 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL2193248 | 0.78 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL1914340 | 0.74 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL1984448 | 0.73 | HCRTR1 (0.33) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119853-A1 | ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-29 | — | — | WO | disclosed |