Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005081 | 1.00 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL1980791 | 0.83 | HCRTR1 (0.35) | — | |
| SCHEMBL16005833 | 0.81 | EPHX1 (0.37) | — | |
| SCHEMBL16005832 | 0.81 | EPHX1 (0.37) | — | |
| SCHEMBL2449259 | 0.78 | LIPG (0.34) | DGAT1 | |
| SCHEMBL2368358 | 0.78 | P2RY14 (0.32) | — | |
| SCHEMBL1914340 | 0.74 | HCRTR1 (0.32) | — | |
| SCHEMBL1984447 | 0.73 | HCRTR1 (0.33) | — | |
| SCHEMBL1984448 | 0.73 | HCRTR1 (0.33) | — | |
| SCHEMBL22798497 | 0.70 | HCRTR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774927-A1 | Inhibitors of HCV NS5A | Presidio Pharmaceuticals, Inc. (US) | 2014-09-10 | — | — | EP | disclosed |