Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31677104 | 1.00 | PSMB8 (0.58) | PSMB8ALDH1A1NPC1RAB9ANPSR1 | |
| Lithium SCHEMBL15812806 | 0.98 | PSMB8 (0.56) | PSMB8ALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL222527 | 0.79 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL3081165 | 0.79 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL718646 | 0.79 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL2162639 | 0.79 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL6209371 | 0.75 | TRPV1 (0.51) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL14629339 | 0.75 | PSMB8 (0.53) | PSMB8ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL14427087 | 0.75 | PSMB8 (0.49) | PSMB8 | |
| SCHEMBL28275372 | 0.73 | TNKS2 (0.56) | ALDH1A1RAB9AKDM4EPKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534620-A | Preparation method of palladium-catalyzed hydrocarbon bond functionalized 2-trifluoromethyl benzimidazole compound | 六盘水师范学院 | 2024-02-09 | — | — | CN | claimed |
| CN-108218832-A | A kind of pyridyl group bridging benzimidazole imine compound and its synthesis | 中国科学院大连化学物理研究所 | 2018-06-29 | — | — | CN | claimed |
| CN-107459508-A | Annelated pyrimidines as the inhibitor of P97 compounds | 克里弗生物科学公司 | 2017-12-12 | — | — | CN | claimed |
| US-9742034-B2 | Cyano-benzimidazole salts for electrochemical cells and method for synthesis thereof | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2017-08-22 | — | — | US | claimed |
| US-20140178771-A1 | CYANO-BENZIMIDAZOLE SALTS FOR ELECTROCHEMICAL CELLS AND METHOD FOR SYNTHESIS THEREOF | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2014-06-26 | — | — | US | claimed |
| US-20020026059-A1 | Benzimidazole derivatives | ASSMANN LUTZ (DE) | 2002-02-28 | — | — | US | claimed |
| CN-1187820-A | Benzimidazole derivatives | BAYER AG (DE) | 1998-07-15 | — | — | CN | claimed |
| EP-0820457-A1 | BENZIMIDAZOLE DERIVATIVES | BAYER AG (DE) | 1998-01-28 | — | — | EP | claimed |
| EP-0517476-B1 | Benzimidazole derivatives, a method for producing the same, agricultural and horticultural fungicides containing the same as an active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL CO (JP) | 1997-10-08 | — | — | EP | claimed |
| US-5571830-A | FUNGICIDES, INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | claimed |
| US-5510364-A | FUNGICIDES, INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | claimed |
| EP-0545204-A1 | 2-cyanobenzimidazoles, process for their preparation and their use in agriculture and new precursors | BAYER AG (DE) | 1993-06-09 | — | — | EP | claimed |
| EP-0517476-A2 | Benzimidazole derivatives, a method for producing the same, agricultural and horticultural fungicides containing the same as an active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | claimed |
| EP-0230844-A1 | Fungicides comprising triazole and oligo ether groups, and mixtures thereof | RHONE-POULENC AGROCHIMIE (FR) | 1987-08-05 | — | — | EP | claimed |
| US-4622323-A | AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1986-11-11 | — | — | US | claimed |
| CN-85107900-A | The preparation of new 2-cyano-benzimidazole derivative and as sterilant and acaricidal purposes | — | 1986-06-10 | — | — | CN | claimed |
| EP-0087375-B1 | CYANO-2-BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR UTILISATION AS FUNGICIDES AND ACARICIDES | RHONE-POULENC AGROCHIMIE (FR) | 1985-09-18 | — | — | EP | claimed |
| US-4536502-A | PESTICIDES, MITICIDES | RHONE-POULENC AGROCHIMIE (FR) | 1985-08-20 | — | — | US | claimed |
| US-4490463-A | SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1984-12-25 | — | — | US | claimed |
| US-4223082-A | ELECTROMAGNETIC WAVES | EASTMAN KODAK COMPANY (US) | 1980-09-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026059-A1 | Benzimidazole derivatives | BAK1, XDH, ZFX | PSMB8 3533/4885ALDH1A1 1032/4885NPC1 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.