Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162639 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL31677104 | 0.79 | PSMB8 (0.58) | ALDH1A1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL244929 | 0.79 | PSMB8 (0.58) | ALDH1A1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL3081165 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL718646 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ENPC1RAB9ANPSR1 | |
| Lithium SCHEMBL15812806 | 0.78 | PSMB8 (0.56) | ALDH1A1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL3147724 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1RAB9APKM | |
| SCHEMBL6209371 | 0.75 | TRPV1 (0.51) | ALDH1A1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL17137745 | 0.75 | SRC (0.44) | KDM4EHSD17B10MEN1KMT2APOLB | |
| SCHEMBL20448748 | 0.73 | PSMB8 (0.70) | ALDH1A1KDM4ENPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | claimed |
| US-11805697-B2 | Organic electroluminescence device and monoamine compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-10-31 | — | — | US | claimed |
| US-20230242529-A1 | HETEROCYCLIC COMPOUND | FIMECS, INC. (JP) | 2023-08-03 | — | — | US | claimed |
| US-11639354-B2 | Heterocyclic compound | FIMECS, INC. (JP) | 2023-05-02 | — | — | US | claimed |
| US-20230066315-A1 | COMPOUNDS AND USES THEREOF | NUVATION BIO OPERATING COMPANY LLC | 2023-03-02 | — | — | US | claimed |
| US-20230055036-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO LTD (KR) | 2023-02-23 | — | — | US | claimed |
| CN-115433203-A | Amine fluorinated curcumenol derivative compound and application and preparation method thereof | 华东理工大学 | 2022-12-06 | — | — | CN | claimed |
| US-20220169648-A1 | 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2022-06-02 | — | — | US | claimed |
| US-11254670-B2 | 1,8-naphthyridinone compounds and uses thereof | NUVATION BIO INC. (US) | 2022-02-22 | — | — | US | claimed |
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | MONASH UNIVERSITY (AU) | 2022-01-18 | — | — | US | claimed |
| US-4808620-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIALLERGENS, ANTIARTHRITIC, ANTIRHEUMATIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-02-28 | — | — | US | claimed |
| EP-0265495-A4 | BONDED PHASE CHROMATOGRAPHIC SUPPORTS. | ANALYTICHEM INT INC (US) | 1988-11-23 | — | — | EP | claimed |
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | claimed |
| EP-0265495-A1 | BONDED PHASE CHROMATOGRAPHIC SUPPORTS | ANALYTICHEM INTERNATIONAL, INC. (US) | 1988-05-04 | — | — | EP | claimed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | claimed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | claimed |
| WO-1987006586-A1 | BONDED PHASE CHROMATOGRAPHIC SUPPORTS | ANALYTICHEM INTERNATIONAL, INC. (US) | 1987-11-05 | — | — | WO | claimed |
| US-4591377-A | Herbicidal esters of 2-bromo-4-methylimidazole-5-carboxylic acid | STAUFFER CHEMICAL COMPANY (US) | 1986-05-27 | — | — | US | claimed |
| US-4025622-A | ANTIBACTERIAL | Ogura, Haruo (JA) | 1977-05-24 | — | — | US | claimed |
| US-4007174-A | Cephalosporin compounds | GLAXO LABORATORIES LIMITED (EN) | 1977-02-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242529-A1 | HETEROCYCLIC COMPOUND | XIAP, BIRC5, BIRC3 | ALDH1A1 2510/4885KDM4E 2577/4885NPC1 2963/4885 |
| US-20230055036-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SLC18A2, SLC18A1, MAOA | ALDH1A1 89/4885KDM4E 1377/4885NPC1 698/4885 |
| US-11254670-B2 | 1,8-naphthyridinone compounds and uses thereof | NME1, ADORA2A, GPR68 | ALDH1A1 1543/4885KDM4E 3184/4885NPC1 2384/4885 |
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | VIP, PNKP, PEPD | ALDH1A1 4859/4885KDM4E 4142/4885NPC1 2542/4885 |
| US-20230066315-A1 | COMPOUNDS AND USES THEREOF | ADORA2A, GRK2, GRK4 | ALDH1A1 1925/4885KDM4E 3737/4885NPC1 2675/4885 |
| US-11805697-B2 | Organic electroluminescence device and monoamine compound for organic electroluminescence device | SLC18A2, SLC18A1, MAOA | ALDH1A1 89/4885KDM4E 1377/4885NPC1 698/4885 |
| US-11639354-B2 | Heterocyclic compound | XIAP, BIRC5, BIRC3 | ALDH1A1 2510/4885KDM4E 2577/4885NPC1 2963/4885 |
| US-20220169648-A1 | 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF | NME1, ADORA2A, GPR68 | ALDH1A1 1543/4885KDM4E 3184/4885NPC1 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.