Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180685 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL1148875 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL1412844 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL777939 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL2221935 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL2113832 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL4846247 | 0.76 | CES1 (0.48) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL27962643 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL777046 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL7670480 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CES2CES1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737429-B2 | TREATMENT OF HIV MEDIATED DISEASES. | HOFFMANN-LA ROCHE INC. | 2004-05-18 | — | — | US | claimed |
| EP-1301481-A1 | PYRROLE DERIVATIVES FOR TREATING AIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-16 | — | — | EP | claimed |
| US-20020032221-A1 | Pyrrole derivatives | ROCHE PRODUCTS LIMITED (GB) | 2002-03-14 | — | — | US | claimed |
| WO-2002002524-A1 | PYRROLE DERIVATIVES FOR TREATING AIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-10 | — | — | WO | claimed |
| EP-1980908-B1 | Use of silver halide photographic material and image forming method | FUJIFILM CORP (JP) | 2011-09-07 | — | — | EP | disclosed |
| US-7592133-B2 | Silver halide photographic material and image forming method using the same | FUJIFILM CORPORATION (JP) | 2009-09-22 | — | — | US | disclosed |
| US-7449500-B2 | Ink jet ink containing multimetallic polymeric colorants | EASTMAN KODAK COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449287-B1 | Pearlescent textured imaging supports | EASTMAN KODAK COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-20080268385-A1 | Silver halide photographic material and image forming method using the same | FUJIFILM CORPORATION (JP) | 2008-10-30 | — | — | US | disclosed |
| EP-1980908-A1 | Silver halide photographic material and image forming method using the same | FUJIFILM Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-0962499-B2 | Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles | CIBA SC HOLDING AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| EP-1740662-B1 | INK JET INK SET | EASTMAN KODAK CO (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-0094911-A2 | Preparation of pyrrolo-(3,4-c) pyrroles | CIBA-GEIGY AG (CH) | 1983-11-23 | — | — | EP | disclosed |
| US-4415685-A | POLYMERIC FLUORESCENT RED DYES; LACQUERS; TONERS; VARNISHES; FIBERS; PLASTICS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1983-11-15 | — | — | US | disclosed |
| EP-0061426-A1 | Process for colouring highly molecular organic material and polycyclic pigments | CIBA-GEIGY AG (CH) | 1982-09-29 | — | — | EP | disclosed |
| US-4022799-A | DYEING, PRINTING OF NATURAL AND SYNTHETIC MATERIALS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-4001253-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3966405-A | N-Alkyl nitro phenyl diethylene triamine dyeing of acid modified synthetic fibers | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
| US-3963436-A | Bis nitrophenyl diethylene triamine dyeing of synthetic acid modified fibers | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-15 | — | — | US | disclosed |
| US-3950347-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032221-A1 | Pyrrole derivatives | PYCR1, SARS1, MAVS | ALDH1A1 2902/4885CES2 1902/4885CES1 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.