Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18982349 | 0.84 | THRB (0.36) | THRBPOLBMAPTMEN1KMT2A | |
| SCHEMBL27755208 | 0.79 | POLB (0.42) | THRBPOLBMAPTMEN1KMT2A | |
| SCHEMBL25532332 | 0.76 | MEN1 (0.33) | THRBMEN1KMT2A | |
| SCHEMBL10518577 | 0.76 | TSHR (0.39) | THRBPOLBMAPTMEN1KMT2A | |
| SCHEMBL12858177 | 0.76 | NUDT1 (0.36) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31591033 | 0.76 | ALDH1A1 (0.45) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL12051523 | 0.76 | ALDH1A1 (0.45) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8394533 | 0.75 | POLB (0.42) | THRBPOLBMAPTMEN1KMT2A | |
| SCHEMBL10649686 | 0.75 | NR1H2 (0.38) | THRBPOLBMAPTMEN1KMT2A | |
| SCHEMBL13165162 | 0.74 | NUDT1 (0.35) | MEN1KMT2ANUDT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120207-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2022-06-09 | — | — | WO | disclosed |