Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18726773 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1HSD17B10PTK2B | |
| SCHEMBL11417303 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1HSD17B10PTK2B | |
| SCHEMBL4545218 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL6836877 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL6622150 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL5641654 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL15804810 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL18726853 | 0.72 | ALDH1A1 (0.48) | SMN1; SMN2LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL15804830 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL5642488 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732899-B1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S R L (IT) | 2011-09-21 | — | — | EP | claimed |
| US-7381823-B2 | Process for preparing cyclohexanediacetic acid monoamide | SERICHIM S.R.L. (IT) | 2008-06-03 | — | — | US | claimed |
| US-20070208175-A1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S.R.L. (IT) | 2007-09-06 | — | — | US | claimed |
| EP-1732899-A2 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHUM S.R.L. (IT) | 2006-12-20 | — | — | EP | claimed |
| WO-2005090310-A2 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S.R.L. (IT) | 2005-09-29 | — | — | WO | claimed |
| EP-1732899-B1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S R L (IT) | 2011-09-21 | — | — | EP | disclosed |
| EP-1732899-B1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S R L (IT) | 2011-09-21 | — | — | EP | disclosed |
| US-7381823-B2 | Process for preparing cyclohexanediacetic acid monoamide | SERICHIM S.R.L. (IT) | 2008-06-03 | — | — | US | disclosed |
| US-20070208175-A1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S.R.L. (IT) | 2007-09-06 | — | — | US | disclosed |
| US-20070208175-A1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S.R.L. (IT) | 2007-09-06 | — | — | US | disclosed |
| EP-1732899-A2 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHUM S.R.L. (IT) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005090310-A2 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S.R.L. (IT) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208175-A1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | GNPAT, GMDS, PIGS | SMN1; SMN2 3584/4885LMNA 3479/4885ALDH1A1 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.