Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | MPO | P05164 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553805 | 0.86 | PSEN1 (0.42) | CYP19A1MPOSLC6A4PSEN1PSEN2 | |
| SCHEMBL24497556 | 0.82 | PSEN1 (0.45) | CYP19A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19980400 | 0.78 | MPO (0.40) | MPOSLC6A4TYR | |
| SCHEMBL20230849 | 0.76 | CYP19A1 (0.44) | CYP19A1MPOSLC6A4PSEN1PSEN2 | |
| SCHEMBL2760306 | 0.73 | PSEN1 (0.44) | CYP19A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26544772 | 0.71 | PSEN1 (0.43) | CYP19A1SLC6A4PSEN1PSEN2APH1B | |
| SCHEMBL24498403 | 0.71 | PSEN1 (0.43) | CYP19A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8978666 | 0.70 | KDM4E (0.40) | MPOSLC6A4TYRMETAP2KDM4E | |
| SCHEMBL13349755 | 0.70 | TYR (0.50) | MPOTYRKDM4E | |
| Hydrochloric Acid SCHEMBL21048779 | 0.70 | CYP19A1 (0.41) | CYP19A1MPOSLC6A4PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |