Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20091675 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL26122242 | 0.76 | CYP19A1 (0.35) | ALDH1A1SMN1; SMN2KMT2ACA2TDP1 | |
| SCHEMBL4679730 | 0.76 | KMT2A (0.38) | ALDH1A1SMN1; SMN2KMT2AHTTTDP1 | |
| SCHEMBL20155932 | 0.75 | RECQL (0.41) | ALDH1A1KMT2AMEN1HTTRECQL | |
| SCHEMBL20073210 | 0.73 | POLB (0.38) | CA2TDP1RECQLGABRA1GABRB2 | |
| SCHEMBL27540668 | 0.72 | ALB (0.47) | ALDH1A1KMT2AMEN1HTTTDP1 | |
| SCHEMBL13145660 | 0.72 | KMT2A (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL18897466 | 0.72 | PKM (0.40) | ALDH1A1CA2HSD11B1SLC22A12TDP1 | |
| SCHEMBL26119628 | 0.71 | KMT2A (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL24497694 | 0.70 | PTK2 (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |