SCHEMBL24499146

SCHEMBL24499146

CN(C)C(=O)C(=O)c1cn(Cc2ccccc2)c2nccc(OCc3ccccc3)c12

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.42
LTB4R2 Q9NPC1 1/20 0.42
PLA2G2A P14555 1/20 0.41
LRRK2 Q5S007 1/20 0.39
MAPK14 Q16539 5/20 0.39
ALKBH1 Q13686 2/20 0.37
BRD4 O60885 2/20 0.37
P2RX7 Q99572 1/20 0.37
PPIA P62937 2/20 0.36
PTGER1 P34995 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29832165 1.00 LTB4R (0.42) LTB4RLTB4R2PLA2G2ALRRK2MAPK14
SCHEMBL25606378 0.90 LTB4R (0.41) LTB4RLTB4R2PLA2G2ALRRK2ALKBH1
SCHEMBL26612358 0.85 LTB4R (0.42) LTB4RLTB4R2PLA2G2AMAPK14ALKBH1
SCHEMBL25606389 0.78 L3MBTL1 (0.35) LTB4RLTB4R2LRRK2ALKBH1ALDH1A1
SCHEMBL25606407 0.76 BRD4 (0.37) LTB4RLTB4R2PLA2G2AALKBH1BRD4
SCHEMBL25606395 0.75 SMN1; SMN2 (0.44) LTB4RLTB4R2ALKBH1BRD4PTGER1
SCHEMBL30368570 0.75 LRRK2 (0.46) LRRK2BRD4PPIA
SCHEMBL24499446 0.75 TDP1 (0.38) LTB4RLTB4R2MAPK14BRD4P2RX7
SCHEMBL23819785 0.74 LTB4R (0.52) LTB4RLTB4R2PLA2G2APTGER1
SCHEMBL23805215 0.70 LTB4R (0.48) LTB4RLTB4R2PLA2G2APTGER1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199543-A1 Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2024-06-20 US disclosed
US-11952342-B2 Aza-substituted psilocin analogs and methods of synthesizing the same MYDECINE INNOVATIONS GROUP INC. (US) 2024-04-09 US disclosed
US-20240101513-A1 Novel Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2024-03-28 US disclosed
US-11939292-B1 Aza-substituted psilocin analogs and methods of synthesizing the same MYDECINE INNOVATIONS GROUP INC. (US) 2024-03-26 US disclosed
US-11939292-B1 Aza-substituted psilocin analogs and methods of synthesizing the same MYDECINE INNOVATIONS GROUP INC. (US) 2024-03-26 US disclosed
US-11939292-B1 Aza-substituted psilocin analogs and methods of synthesizing the same MYDECINE INNOVATIONS GROUP INC. (US) 2024-03-26 US disclosed
US-20230348380-A1 Novel Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2023-11-02 US disclosed
US-20230348380-A1 Novel Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2023-11-02 US disclosed
US-20230348380-A1 Novel Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2023-11-02 US disclosed
EP-4255422-A1 NOVEL PSILOCIN ANALOG COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME Mydecine Innovations Group Inc. (US) 2023-10-11 EP disclosed
US-20230271924-A1 Novel Psilocin Analog Compositions And Methods of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2023-08-31 US disclosed
US-20230271924-A1 Novel Psilocin Analog Compositions And Methods of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2023-08-31 US disclosed
US-20230271924-A1 Novel Psilocin Analog Compositions And Methods of Synthesizing The Same MYDECINE INNOVATIONS GROUP INC. 2023-08-31 US disclosed
WO-2023101722-A1 NOVEL AZA-SUBSTITUTED PSILOCIN ANALOGS AND METHODS OF SYNTHESIZING THE SAME MEDECINE INNOVATIONS GROUP INC. (US) 2023-06-08 WO disclosed
WO-2023101722-A1 NOVEL AZA-SUBSTITUTED PSILOCIN ANALOGS AND METHODS OF SYNTHESIZING THE SAME MEDECINE INNOVATIONS GROUP INC. (US) 2023-06-08 WO disclosed
WO-2022120181-A1 NOVEL PSILOCIN ANALOG COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME MYDECINE INNOVATIONS GROUP INC. (US) 2022-06-09 WO disclosed
WO-2022120181-A1 NOVEL PSILOCIN ANALOG COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME MYDECINE INNOVATIONS GROUP INC. (US) 2022-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101513-A1 Novel Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same TOP2A, PAICS, TOP1 LTB4R 3523/4885LTB4R2 3775/4885PLA2G2A 979/4885
US-20230348380-A1 Novel Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same TOP2A, PAICS, TOP1 LTB4R 3523/4885LTB4R2 3775/4885PLA2G2A 979/4885
US-11952342-B2 Aza-substituted psilocin analogs and methods of synthesizing the same TOP2A, PAICS, TOP1 LTB4R 4033/4885LTB4R2 4217/4885PLA2G2A 1215/4885
US-20230271924-A1 Novel Psilocin Analog Compositions And Methods of Synthesizing The Same PSAP, ABCG2, PSAT1 LTB4R 2989/4885LTB4R2 2950/4885PLA2G2A 405/4885
US-20240199543-A1 Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same TOP2A, PAICS, TOP1 LTB4R 4033/4885LTB4R2 4217/4885PLA2G2A 1215/4885
US-11939292-B1 Aza-substituted psilocin analogs and methods of synthesizing the same TOP2A, PAICS, TOP1 LTB4R 4033/4885LTB4R2 4217/4885PLA2G2A 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.