Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18403094 | 0.89 | ESR1 (0.60) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL20080439 | 0.82 | ESR1 (0.52) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL9973089 | 0.80 | ALDH1A1 (0.80) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL822829 | 0.80 | ESR1 (0.80) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL12893281 | 0.80 | ESR1 (0.80) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL5452904 | 0.78 | ESR1 (0.48) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL13879208 | 0.78 | ESR1 (0.48) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL21168792 | 0.78 | ESR1 (0.48) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL2534363 | 0.78 | ESR1 (0.48) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL12306231 | 0.78 | ESR1 (0.48) | ESR1ESR2ALDH1A1L3MBTL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177641-A1 | CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND | TOKYO OHKA KOGYO CO., LTD. (JP) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177641-A1 | CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND | CROCC, RCSD1, WDR5 | ESR1 3744/4885ESR2 2593/4885ALDH1A1 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.