Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.80 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.80 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.44 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12893281 | 1.00 | ESR1 (0.80) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL13601646 | 0.98 | ESR1 (0.79) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL12755223 | 0.90 | ESR1 (0.65) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL13379654 | 0.89 | ESR2 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL2132163 | 0.89 | ESR2 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL13379656 | 0.89 | ESR2 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL2131554 | 0.89 | ESR2 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL10777847 | 0.89 | ESR2 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL13379655 | 0.89 | ESR2 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL13379657 | 0.89 | ESR2 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180216008-A1 | HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-9902706-B2 | Process for making benzoxazines | CYTEC INDUSTRIES INC. (US) | 2018-02-27 | — | — | US | disclosed |
| US-20170369679-A1 | NOR-HALS COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9790367-B2 | Polycarbonate compositions for reduced splay in combination with sustained or improved impact resistance | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-10-17 | — | — | US | disclosed |
| US-9783655-B2 | NOR-HALS compounds as flame retardants | BASF SE (DE) | 2017-10-10 | — | — | US | disclosed |
| US-20170190907-A1 | HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-07-06 | — | — | US | disclosed |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-15 | — | — | US | disclosed |
| US-20170158853-A1 | HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | US | disclosed |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | US | disclosed |
| US-20170037243-A1 | HIGH HEAT POLYCARBONATE COMPOSITIONS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-02-09 | — | — | US | disclosed |
| US-7923525-B2 | Polyester resin and fabrication method thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-04-12 | — | — | US | disclosed |
| US-20110046237-A1 | COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046237-A1 | COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-7825265-B2 | di-aromatic compounds for treatment and prevention of diseases and disorders related to estrogen receptors; 2-fluoro-1-methoxy-4-(1-phenyl-cyclohexyl)-benzene | ACADIA PHARMACEUTICALS INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-7825265-B2 | di-aromatic compounds for treatment and prevention of diseases and disorders related to estrogen receptors; 2-fluoro-1-methoxy-4-(1-phenyl-cyclohexyl)-benzene | ACADIA PHARMACEUTICALS INC. (US) | 2010-11-02 | — | — | US | disclosed |
| WO-2009072002-A2 | BISPHENOLS IN CANCER THERAPY | UNIVERSITY OF MANITOBA (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2008033894-A2 | COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| US-7297456-B2 | Photoconductors containing crosslinked polycarbonate polymers | XEROX CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |
| US-7229732-B2 | Imaging members with crosslinked polycarbonate in charge transport layer | XEROX CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |
| WO-2007056500-A2 | COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180216008-A1 | HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS | PFAS, PCBP1, DDT | ESR1 2299/4885ESR2 2354/4885ACHE 3300/4885 |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, EPHX2 | ESR1 199/4885ESR2 138/4885ACHE 2475/4885 |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, HSPBP1 | ESR1 2714/4885ESR2 2596/4885ACHE 2333/4885 |
| US-20110046237-A1 | COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS | ESR2, ESR1, GPER1 | ESR1 2/4885ESR2 1/4885ACHE 1943/4885 |
| US-20170369679-A1 | NOR-HALS COMPOUNDS AS FLAME RETARDANTS | PFAS, NONO, PARG | ESR1 4170/4885ESR2 3543/4885ACHE 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.