Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14926556 | 0.84 | NOTUM (0.39) | RAPGEF4NOTUMNISCHGPR35CA12 | |
| SCHEMBL17514549 | 0.81 | RAPGEF4 (0.48) | RAPGEF4ACHENFE2L2 | |
| SCHEMBL13986747 | 0.80 | RAPGEF4 (0.42) | DHODHRAPGEF4ACHENFE2L2 | |
| SCHEMBL10014275 | 0.80 | RAPGEF4 (0.42) | DHODHRAPGEF4ACHENFE2L2 | |
| SCHEMBL10018717 | 0.80 | HDAC1 (0.39) | DHODHRAPGEF4ACHENFE2L2 | |
| SCHEMBL10018706 | 0.80 | ACHE (0.43) | DHODHACHENFE2L2 | |
| SCHEMBL17943190 | 0.78 | NFE2L2 (0.42) | DHODHACHENFE2L2 | |
| SCHEMBL1043323 | 0.78 | ACHE (0.48) | RAPGEF4ACHENFE2L2 | |
| SCHEMBL20261216 | 0.78 | SELL (0.40) | RAPGEF4ACHENFE2L2 | |
| SCHEMBL17515038 | 0.76 | NFE2L2 (0.32) | DHODHNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117551-A1 | LIQUID CRYSTALLINE MEDIUM AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2022-06-09 | — | — | WO | disclosed |