Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GRK2 | P25098 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765898 | 0.83 | SMN1; SMN2 (0.57) | KMT2AMEN1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL2374142 | 0.83 | MEN1 (0.80) | KMT2AMEN1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL2322923 | 0.82 | KMT2A (0.53) | KMT2AMEN1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL14721362 | 0.82 | ALDH1A1 (0.52) | KMT2AMEN1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL30362093 | 0.82 | LTB4R (0.64) | KMT2AMEN1NPSR1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9487751 | 0.82 | RAD52 (0.62) | KMT2AMEN1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL15754270 | 0.82 | LTB4R (0.64) | KMT2AMEN1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3880123 | 0.81 | MAPT (0.51) | KMT2AMEN1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL1241796 | 0.81 | KMT2A (0.51) | KMT2AMEN1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL24825616 | 0.79 | CYP1A2 (0.53) | KMT2AMEN1NPSR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034727-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | Stingray Therapeutics, Inc. | 2024-02-01 | — | — | US | disclosed |
| CN-116963733-A | Imidazole compounds as ENPP1 inhibitors | 斯汀格瑞治疗股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-4255425-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | Stingray Therapeutics, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022119928-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | Stingray Therapeutics, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022119928-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | Stingray Therapeutics, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240034727-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | ENPP1, PPP1R1B, PPM1B | KMT2A 2718/4885MEN1 231/4885NPSR1 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.