Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29830601 | 1.00 | GABRA2 (0.47) | GABRA2GABRB2TP53MDM2ALDH1A1 | |
| SCHEMBL24500641 | 0.90 | TSHR (0.43) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL31678415 | 0.90 | TSHR (0.43) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL31678221 | 0.88 | ALDH1A1 (0.42) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL24501182 | 0.88 | ALDH1A1 (0.42) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL24501091 | 0.85 | POLB (0.41) | TP53ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29830842 | 0.85 | POLB (0.41) | TP53ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10463694 | 0.84 | AR (0.57) | GABRA2GABRB2TP53MDM2ALDH1A1 | |
| SCHEMBL31678341 | 0.83 | APAF1 (0.41) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL24500632 | 0.83 | APAF1 (0.41) | GABRA2GABRB2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547273-A | Herbicidal derivatives | 先正达农作物保护股份公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022117445-A1 | HERBICIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-09 | — | — | WO | disclosed |