Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306525 | 1.00 | CTSL (0.38) | CTSLCTSKKCNH2AKT1 | |
| SCHEMBL21936392 | 0.81 | KCNH2 (0.34) | KCNH2AKT1 | |
| SCHEMBL21069201 | 0.78 | — | — | |
| SCHEMBL1712693 | 0.78 | — | — | |
| SCHEMBL24615140 | 0.78 | — | — | |
| SCHEMBL1307610 | 0.78 | VCP (0.35) | CTSLCTSK | |
| SCHEMBL3630604 | 0.78 | VCP (0.35) | CTSLCTSK | |
| SCHEMBL1306470 | 0.75 | KMT2A (0.35) | CTSLCTSK | |
| SCHEMBL31679143 | 0.73 | CTSL (0.38) | CTSLCTSK | |
| SCHEMBL8147635 | 0.73 | SLC18A3 (0.35) | CTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |