Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24506792 | 0.75 | HTR1D (0.33) | — | |
| SCHEMBL26141817 | 0.73 | BRD4 (0.33) | — | |
| SCHEMBL13084175 | 0.73 | PRMT1 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12702833 | 0.69 | KCNH2 (0.32) | NPC1SCN4ARAB9ASMN1; SMN2 | |
| SCHEMBL10199417 | 0.69 | NPC1 (0.44) | NPC1SCN4ARAB9ASMN1; SMN2 | |
| SCHEMBL18719687 | 0.68 | CHRNA7 (0.37) | NPC1SCN4ARAB9ASMN1; SMN2 | |
| SCHEMBL18719676 | 0.67 | GABRA1 (0.36) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL22583050 | 0.67 | CHRNA7 (0.36) | SMN1; SMN2 | |
| SCHEMBL13356662 | 0.66 | PDGFRB (0.42) | — | |
| SCHEMBL24506581 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
| US-20220185792-A1 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185792-A1 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | NPC1 2525/4885SCN4A 4223/4885RAB9A 1027/4885 |
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | NPC1 2525/4885SCN4A 4223/4885RAB9A 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.