Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 4/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24506573 | 0.76 | PRMT1 (0.30) | PRMT1 | |
| SCHEMBL16125098 | 0.72 | CKS1B (0.39) | CKS1BSKP1SKP2METPTPN11 | |
| SCHEMBL16571572 | 0.68 | NCF1 (0.37) | CKS1BSKP1SKP2 | |
| SCHEMBL16571761 | 0.66 | NPC1 (0.40) | GRM5 | |
| SCHEMBL7309780 | 0.65 | DYRK1A (0.36) | — | |
| SCHEMBL9109279 | 0.65 | PRMT1 (0.41) | PRMT1 | |
| SCHEMBL17676271 | 0.65 | PDGFRB (0.46) | CKS1BSKP1SKP2 | |
| SCHEMBL24506571 | 0.64 | TGFBR1 (0.38) | — | |
| SCHEMBL7048629 | 0.62 | NCF1 (0.55) | CKS1BSKP1SKP2MET | |
| Hydrochloric Acid SCHEMBL28590788 | 0.60 | NCF1 (0.53) | CKS1BSKP1SKP2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
| US-20220185792-A1 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185792-A1 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | CKS1B 959/4885SKP1 2165/4885SKP2 347/4885 |
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | CKS1B 959/4885SKP1 2165/4885SKP2 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.