⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24506567 | 0.78 | — | — | |
| SCHEMBL24506573 | 0.77 | PRMT1 (0.30) | — | |
| SCHEMBL25793171 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL24506565 | 0.72 | HTR1D (0.33) | — | |
| SCHEMBL24506581 | 0.72 | — | — | |
| SCHEMBL24506894 | 0.67 | BACE1 (0.38) | — | |
| SCHEMBL26795835 | 0.66 | PIK3CG (0.34) | — | |
| SCHEMBL24506796 | 0.65 | ALDH1A1 (0.37) | — | |
| SCHEMBL25793198 | 0.64 | — | — | |
| SCHEMBL24506887 | 0.61 | NOS3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
| US-20220185792-A1 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-06-16 | — | — | US | disclosed |