Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24506818 | 0.74 | KDM4E (0.50) | HSD17B10ALDH1A1 | |
| SCHEMBL24506782 | 0.72 | HSD17B10 (0.35) | HSD17B10FGFR1 | |
| SCHEMBL25793171 | 0.71 | ALDH1A1 (0.35) | HSD17B10DHFRALDH1A1NUDT1FGFR1 | |
| SCHEMBL25793169 | 0.71 | FGFR1 (0.41) | ALDH1A1NUDT1FGFR1 | |
| SCHEMBL24506563 | 0.69 | GAA (0.40) | DHFRALDH1A1NUDT1 | |
| SCHEMBL25449339 | 0.68 | ALDH1A1 (0.35) | HSD17B10DHFRALDH1A1NUDT1FGFR1 | |
| SCHEMBL24506811 | 0.67 | ALDH1A1 (0.46) | HSD17B10ALDH1A1 | |
| SCHEMBL5513652 | 0.66 | HSD17B10 (0.48) | HSD17B10ALDH1A1 | |
| SCHEMBL18007575 | 0.66 | HSD17B10 (0.72) | HSD17B10 | |
| SCHEMBL12776073 | 0.65 | UHRF1 (0.38) | HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
| US-20220185792-A1 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185792-A1 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | HSD17B10 2879/4885DHFR 1550/4885ALDH1A1 4228/4885 |
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | HSD17B10 2879/4885DHFR 1550/4885ALDH1A1 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.