Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 12/20 | 0.41 |
| ▸ | SRC | P12931 | 8/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23456596 | 0.77 | TSHR (0.32) | ALDH1A1 | |
| SCHEMBL24506567 | 0.75 | — | — | |
| SCHEMBL22521384 | 0.75 | KDM4E (0.43) | ALDH1A1 | |
| SCHEMBL25793171 | 0.74 | ALDH1A1 (0.35) | FGFR1SRCPDGFRBPDGFRAALDH1A1 | |
| SCHEMBL25449342 | 0.74 | LCK (0.36) | SRCCLK1DYRK1ANUDT1PRKD3 | |
| SCHEMBL2319759 | 0.74 | FGFR1 (0.42) | FGFR1SRCALDH1A1CLK1DYRK1A | |
| SCHEMBL24506861 | 0.72 | FGFR1 (0.41) | FGFR1SRCPDGFRBPDGFRAEGFR | |
| SCHEMBL26797949 | 0.72 | EGFR (0.36) | EGFR | |
| SCHEMBL24506820 | 0.71 | HSD17B10 (0.39) | FGFR1ALDH1A1NUDT1 | |
| SCHEMBL24506810 | 0.70 | DCPS (0.41) | ALDH1A1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | FGFR1 4301/4885SRC 2119/4885PDGFRB 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.