Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22458751 | 0.86 | ALOX15 (0.39) | PPARGPPARAALOX15HIF1AEPAS1 | |
| SCHEMBL22459188 | 0.82 | MEN1 (0.44) | ALOX15HIF1AEPAS1 | |
| SCHEMBL22458652 | 0.75 | CES2 (0.40) | — | |
| SCHEMBL19557869 | 0.72 | TRPV1 (0.46) | — | |
| SCHEMBL19987501 | 0.72 | CNR2 (0.42) | — | |
| SCHEMBL28913939 | 0.71 | MMP1 (0.54) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL19387999 | 0.71 | CNR2 (0.35) | ALOX15HIF1AEPAS1 | |
| SCHEMBL31556506 | 0.70 | CES2 (0.43) | — | |
| SCHEMBL17223947 | 0.69 | CNR2 (0.49) | — | |
| SCHEMBL22458722 | 0.69 | NR4A1 (0.46) | NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125925-A1 | COMPOSITIONS FOR TREATING DRY AGE-RELATED MACULAR DEGENERATION (AMD) | COGNITION THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |