Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945545 | 0.84 | GNAI3 (0.35) | L3MBTL1CARM1PRMT6GNAI3GNAO1 | |
| SCHEMBL23560317 | 0.78 | HRH3 (0.31) | — | |
| SCHEMBL26403283 | 0.75 | GNAO1 (0.44) | GNAI3GNAO1GNAI1 | |
| SCHEMBL23695937 | 0.74 | — | — | |
| SCHEMBL26369103 | 0.73 | GNAO1 (0.38) | GNAO1 | |
| SCHEMBL27317530 | 0.72 | CARM1 (0.64) | L3MBTL1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23945810 | 0.72 | L3MBTL1 (0.57) | L3MBTL1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25043635 | 0.72 | HRH3 (0.44) | — | |
| SCHEMBL23568463 | 0.71 | L3MBTL1 (0.44) | L3MBTL1CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL22544374 | 0.71 | L3MBTL1 (0.51) | L3MBTL1CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |