Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703778 | 0.79 | CA12 (0.43) | SMN1; SMN2PTGS1PTGS2HTT | |
| SCHEMBL27334043 | 0.78 | DHFR (0.39) | DHFRTSHRSMN1; SMN2TDP1PTGS1 | |
| SCHEMBL9865417 | 0.75 | SMN1; SMN2 (0.37) | DHFRTSHRSMN1; SMN2TDP1PTGS1 | |
| SCHEMBL29703690 | 0.75 | GAA (0.44) | SMN1; SMN2PKMALDH1A1HPGD | |
| SCHEMBL2996719 | 0.75 | MAPT (0.45) | SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL16549739 | 0.72 | PKM (0.55) | DHFRTSHRSMN1; SMN2TDP1PTGS1 | |
| SCHEMBL30253017 | 0.72 | LOX (0.41) | SMN1; SMN2PTGS2ALDH1A1GRM5HPGD | |
| SCHEMBL27698215 | 0.72 | CASR (0.37) | TSHRSMN1; SMN2TDP1PTGS1PTGS2 | |
| SCHEMBL1404067 | 0.72 | LOX (0.41) | SMN1; SMN2PTGS2ALDH1A1GRM5HPGD | |
| Hydrochloric Acid SCHEMBL28231028 | 0.71 | CASR (0.36) | TSHRSMN1; SMN2TDP1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| EP-2585451-A2 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | Bayer Intellectual Property GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| WO-2012000896-A2 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012000896-A2 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | DHFR 297/4885TSHR 2376/4885SMN1; SMN2 2852/4885 |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | DHFR 297/4885TSHR 2376/4885SMN1; SMN2 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.