Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635714 | 0.84 | EGLN1 (0.54) | SMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL23448916 | 0.81 | PKM (0.55) | MAOBMAOASMN1; SMN2MMP9 | |
| SCHEMBL6297783 | 0.80 | BCHE (0.65) | PTPN1SMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL30130002 | 0.80 | MAOA (0.60) | PTPN1MAOBMAOASMN1; SMN2HDAC1 | |
| SCHEMBL19494569 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2CACNA1HCACNA1BCACNA1CBCHE | |
| SCHEMBL23459076 | 0.79 | CACNA1H (0.51) | PTPN1SMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL29919434 | 0.79 | CACNA1H (0.51) | PTPN1SMN1; SMN2CACNA1HCACNA1BCACNA1C | |
| SCHEMBL23731882 | 0.79 | CACNA1H (0.53) | SMN1; SMN2CACNA1HCACNA1BCACNA1CHDAC1 | |
| SCHEMBL15243340 | 0.79 | CACNA1H (0.53) | SMN1; SMN2CACNA1HCACNA1BCACNA1CBCHE | |
| SCHEMBL15584671 | 0.79 | CACNA1H (0.53) | PTPN1SMN1; SMN2CACNA1HCACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279636-A | Methods and compounds for modulating myotonic muscular dystrophy type 1 | 设计治疗公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |