Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 7/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21818644 | 0.84 | PBRM1 (0.45) | OGTF2CFDMAOAHCRTR1 | |
| SCHEMBL17858066 | 0.83 | OGT (0.43) | OGTF2CFDHCRTR1HCRTR2 | |
| SCHEMBL16174269 | 0.82 | CREBBP (0.49) | OGTKDM4ECREBBP | |
| SCHEMBL434293 | 0.76 | OGT (0.50) | OGTF2CFDCYP1A2 | |
| SCHEMBL17261322 | 0.75 | HTR1A (0.50) | OGTHCRTR1HCRTR2GRM5KDM4E | |
| SCHEMBL4319002 | 0.74 | OGT (0.48) | OGTMAOBF2CFDMAOA | |
| SCHEMBL13681605 | 0.74 | OGT (0.52) | OGTF2CFDKDM4ECYP1A2 | |
| SCHEMBL24512761 | 0.73 | CREBBP (0.34) | OGTMAOBMAOAKDM4ECA12 | |
| SCHEMBL9610681 | 0.73 | EPHX2 (0.39) | OGTF2CFDCREBBPSCN9A | |
| SCHEMBL24512550 | 0.72 | ALDH1A1 (0.39) | MAOBMAOAHCRTR1HCRTR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088827-A | Structure, preparation method and application of hydroxychalcone alkylene derivative | 北京秦天科技集团有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116947776-A | Hydroxy chalcone carboxyl derivative, preparation method and application thereof | 北京秦天科技集团有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20220185815-A1 | PYRROLOPYRAZOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185815-A1 | PYRROLOPYRAZOLE DERIVATIVE | PTDSS1, PTDSS2, SMPD1 | OGT 4456/4885MAOB 4731/4885F2 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.