Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455385 | 0.77 | CA12 (0.49) | CA12CA1CA9PREP | |
| SCHEMBL7414813 | 0.69 | CA12 (0.38) | CA12CA1CA9PREP | |
| SCHEMBL26144375 | 0.66 | CA12 (0.37) | CA12CA1CA9PREP | |
| SCHEMBL17318153 | 0.65 | CA12 (0.47) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL25627201 | 0.64 | CA12 (0.38) | CA12CA1CA9PREP | |
| SCHEMBL5701810 | 0.64 | MAOB (0.47) | CA12CA1CA9PREP | |
| SCHEMBL22079572 | 0.64 | CA12 (0.48) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL1984913 | 0.64 | CA1 (0.35) | CA12CA1CA9PREP | |
| SCHEMBL31026537 | 0.64 | CA12 (0.36) | CA12CA1CA9PREP | |
| SCHEMBL16223358 | 0.63 | CA12 (0.40) | CA12CA1CA9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540322-B2 | MIF modulators | YALE UNIVERSITY (US) | 2017-01-10 | — | — | US | disclosed |
| US-20120004261-A1 | MIF MODULATORS | YALE UNIVERSITY (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004261-A1 | MIF MODULATORS | MIF, HMGB2, HMGB3 | CA12 3086/4885CA1 4164/4885CA9 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.