Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24516489 | 0.80 | DDB1 (0.49) | DDB1CRBNCYP19A1MEN1NPC1 | |
| SCHEMBL8329714 | 0.75 | HTR2C (0.54) | DDB1CRBNHTR2CGID4MEN1 | |
| SCHEMBL21286784 | 0.75 | DDB1 (0.67) | DDB1CRBNHTR2CCYP19A1GID4 | |
| SCHEMBL23705886 | 0.75 | HTR2C (0.58) | DDB1CRBNHTR2CCYP19A1NPC1 | |
| SCHEMBL23676966 | 0.74 | HTR2C (0.61) | DDB1CRBNHTR2CMEN1NPC1 | |
| SCHEMBL1515134 | 0.73 | HTR2C (0.77) | DDB1CRBNHTR2CGID4HTR2A | |
| SCHEMBL30997824 | 0.73 | HTR2C (0.77) | DDB1CRBNHTR2CGID4HTR2A | |
| SCHEMBL317559 | 0.73 | GID4 (0.63) | DDB1CRBNHTR2CCYP19A1GID4 | |
| SCHEMBL10938628 | 0.73 | MAPT (0.43) | DDB1CRBNCYP19A1KMT2ALMNA | |
| SCHEMBL24516525 | 0.73 | SLC6A4 (0.46) | HTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122975-A1 | CYCLOPENTENONES DERIVATIVES AND THEIR USE AS ANTIBIOTICS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-06-16 | — | — | WO | disclosed |