Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073158 | 0.86 | TSHR (0.46) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL13879034 | 0.84 | TSHR (0.50) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL94906 | 0.81 | TSHR (0.68) | TSHRALDH1A1THRBKDM4EUSP2 | |
| SCHEMBL15501945 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1THRB | |
| SCHEMBL15501728 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1THRB | |
| SCHEMBL23369734 | 0.80 | ADRB2 (0.54) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL19998240 | 0.79 | TSHR (0.65) | TSHRALDH1A1THRBKDM4EUSP2 | |
| SCHEMBL3408548 | 0.78 | TSHR (0.50) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL21475876 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1 | |
| SCHEMBL347487 | 0.76 | TSHR (0.61) | TSHRALDH1A1THRBKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11364480-B2 | Chromatography medium with bound microglobules and method for the preparation thereof | SARTORIUS STEDIM BIOTECH GMBH (DE) | 2022-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11364480-B2 | Chromatography medium with bound microglobules and method for the preparation thereof | NEFM, CD68, MLEC | TSHR 4491/4885ALDH1A1 4741/4885ADRB2 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.