Ethyl Benzoate

Ethyl Benzoate

SCHEMBL2451972

CCN(C)C.CCOC(=O)c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.59
RAB9A P51151 4/20 0.59
NPC1 O15118 3/20 0.59
GAA P10253 2/20 0.59
LMNA P02545 2/20 0.59
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
ESR1 P03372 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
ESR2 Q92731 1/20 0.56
CA14 Q9ULX7 1/20 0.56
TSHR P16473 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP3A4 P08684 1/20 0.55
MAOA P21397 1/20 0.55
ALDH1A1 P00352 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Benzoate SCHEMBL21531031 0.92 LMNA (0.63) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL25388294 0.90 LMNA (0.70) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL55674 0.90 LMNA (0.70) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL2762273 0.90 LMNA (0.70) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL29554608 0.88 LMNA (0.68) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL10340677 0.88 LMNA (0.68) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL1404143 0.88 LMNA (0.68) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL28871046 0.88 LMNA (0.68) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL9345283 0.88 LMNA (0.68) SMN1; SMN2RAB9ANPC1GAALMNA
Ethyl Benzoate SCHEMBL595705 0.88 LMNA (0.68) SMN1; SMN2RAB9ANPC1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026295-B2 Curable acrylic mixture including a hindered amine light stabilizer having a 4-Amino-2,2,6,6-tetramethylpiperidin-1 oxyl moiety linked to an acrylic moiety so as to polymerize with the primary resin DENTSPLY INTERNATIONAL, INC. (US) 2011-09-27 US disclosed
US-20080103229-A1 Dental composition with improved light stability WALZ UWE 2008-05-01 US disclosed
EP-1563821-B1 Dental composition with light stability DENTSPLY INT INC (US) 2006-11-22 EP disclosed
EP-1255524-B1 DENTAL COMPOSITION WITH LIGHT STABILITY DENTSPLY INT INC (US) 2005-12-21 EP disclosed
EP-1563821-A1 Dental composition with light stability DENTSPLY INTERNATIONAL, INC. (US) 2005-08-17 EP disclosed
US-20040225029-A1 Dental composition with improved light stability WALZ UWE (US) 2004-11-11 US disclosed
US-20030225182-A1 Dental composition with improved light stability DENTSPLY DETREY GMBH 2003-12-04 US disclosed
EP-1255524-A1 DENTAL COMPOSITION WITH LIGHT STABILITY DENTSPLY INTERNATIONAL, INC. (US) 2002-11-13 EP disclosed
US-20020002213-A1 Dental composition with improved light stability WALZ UWE (DE) 2002-01-03 US disclosed
WO-2001060322-A1 DENTAL COMPOSITION WITH LIGHT STABILITY DENTSPLY INTERNATIONAL INC. (US) 2001-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225182-A1 Dental composition with improved light stability RARA, MAP1LC3A, MAP1LC3C SMN1; SMN2 1366/4885RAB9A 1444/4885NPC1 4466/4885
US-20080103229-A1 Dental composition with improved light stability RARA, MAP1LC3A, MAP1LC3C SMN1; SMN2 1366/4885RAB9A 1444/4885NPC1 4466/4885
US-20020002213-A1 Dental composition with improved light stability MAP1LC3A, RARA, MAP1LC3C SMN1; SMN2 1343/4885RAB9A 1392/4885NPC1 4480/4885
US-20040225029-A1 Dental composition with improved light stability RARA, MAP1LC3A, MAP1LC3C SMN1; SMN2 1366/4885RAB9A 1444/4885NPC1 4466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.