Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | CBX7 | O95931 | 1/20 | 0.31 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.31 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521435 | 0.78 | ALDH1A1 (0.40) | CPN1CPB2 | |
| SCHEMBL24521409 | 0.76 | CPN1 (0.40) | CPN1CPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL18909457 | 0.70 | ALDH1A1 (0.42) | NPY5R | |
| SCHEMBL15808501 | 0.68 | L3MBTL3 (0.51) | CPN1CPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL18428943 | 0.68 | L3MBTL3 (0.35) | CBX7CDYL2CDYLCHRM1CHRM3 | |
| SCHEMBL18909095 | 0.65 | EPHX2 (0.42) | NPY5R | |
| SCHEMBL22891239 | 0.65 | ALDH1A1 (0.39) | — | |
| SCHEMBL22030936 | 0.65 | ALDH1A1 (0.40) | — | |
| SCHEMBL24521449 | 0.64 | CPN1 (0.47) | CPN1CPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL19259598 | 0.64 | KMT2A (0.37) | CBX7CDYL2CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596072-B1 | PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2022-06-22 | — | — | EP | disclosed |