Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909095 | 0.86 | EPHX2 (0.42) | ALDH1A1KMT2ALMNASMN1; SMN2ATM | |
| SCHEMBL19259598 | 0.84 | KMT2A (0.37) | ALDH1A1KMT2ALMNASMN1; SMN2ATM | |
| SCHEMBL22030913 | 0.82 | CYP3A4 (0.41) | ALDH1A1KMT2ALMNASMN1; SMN2ATM | |
| SCHEMBL21281226 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNASMN1; SMN2ATM | |
| SCHEMBL15808501 | 0.80 | L3MBTL3 (0.51) | CPN1CPB2ALDH1A1NPC1L3MBTL3 | |
| SCHEMBL24244805 | 0.77 | EPHX2 (0.40) | ALDH1A1KMT2ALMNASMN1; SMN2ATM | |
| SCHEMBL18909110 | 0.77 | EPHX2 (0.40) | ALDH1A1KMT2ALMNASMN1; SMN2ATM | |
| SCHEMBL24521456 | 0.76 | CPN1 (0.36) | CPN1CPB2CDYLGNAI3GNAO1 | |
| SCHEMBL22030318 | 0.74 | CYP3A4 (0.39) | ALDH1A1KMT2ALMNASMN1; SMN2ATM | |
| SCHEMBL21280987 | 0.74 | KMT2A (0.41) | ALDH1A1KMT2ALMNASMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596072-B1 | PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2022-06-22 | — | — | EP | disclosed |