Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521575 | 0.82 | MEN1 (0.47) | MEN1KMT2AEPHX2CNR1CNR2 | |
| SCHEMBL24521564 | 0.82 | MEN1 (0.47) | MEN1KMT2AEPHX2CNR1CNR2 | |
| SCHEMBL24521558 | 0.71 | MEN1 (0.54) | MEN1KMT2AEPHX2TRPV1CYP1A2 | |
| SCHEMBL27858969 | 0.69 | EPHX2 (0.62) | MEN1KMT2AEPHX2CNR1CNR2 | |
| SCHEMBL24521599 | 0.69 | MEN1 (0.59) | MEN1KMT2AEPHX2P2RX7CYP2C19 | |
| SCHEMBL24521507 | 0.69 | EPHX2 (0.62) | MEN1KMT2AEPHX2TRPV1POLB | |
| SCHEMBL23135875 | 0.68 | TAOK1 (0.53) | MEN1KMT2AEPHX2CNR1CNR2 | |
| SCHEMBL24521563 | 0.67 | KMT2A (0.54) | MEN1KMT2AEPHX2CNR1CNR2 | |
| SCHEMBL18438726 | 0.67 | MEN1 (0.57) | MEN1KMT2AEPHX2P2RX7CYP1A2 | |
| SCHEMBL3474671 | 0.66 | EPHX2 (0.60) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |