Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.66 |
| ▸ | CTSK | P43235 | 10/20 | 0.66 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052278 | 1.00 | CTSS (0.66) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL24521573 | 0.89 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL29052547 | 0.89 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL29052292 | 0.88 | CTSS (0.53) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL24521579 | 0.88 | CTSS (0.53) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL3735628 | 0.87 | CTSS (0.63) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL3735627 | 0.87 | CTSS (0.63) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL3729929 | 0.86 | CTSS (0.59) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL3729927 | 0.86 | CTSS (0.59) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL3729928 | 0.86 | CTSS (0.59) | CTSSCTSKCTSBCTSLPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583497-A | N-benzyl-alpha-aminoamides as late promoting complex/loop (APC/C) inhibitors | 科学研究高级委员会(CSIC) | 2023-08-11 | — | — | CN | disclosed |
| WO-2022129397-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |