Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.53 |
| ▸ | CTSK | P43235 | 8/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521579 | 1.00 | CTSS (0.53) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL24521561 | 0.90 | CTSS (0.51) | CTSSCTSKCTSBCTSLHTRA1 | |
| SCHEMBL29052272 | 0.90 | CTSS (0.51) | CTSSCTSKCTSBCTSLHTRA1 | |
| SCHEMBL24521571 | 0.88 | CTSS (0.66) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL29052278 | 0.88 | CTSS (0.66) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL24521600 | 0.85 | SCN9A (0.53) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL29052629 | 0.85 | SCN9A (0.53) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL14343235 | 0.79 | ITGB3 (0.65) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL1087185 | 0.79 | ITGB3 (0.65) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL16909032 | 0.79 | ITGB3 (0.65) | CTSSCTSKCTSBCTSLPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583497-A | N-benzyl-alpha-aminoamides as late promoting complex/loop (APC/C) inhibitors | 科学研究高级委员会(CSIC) | 2023-08-11 | — | — | CN | disclosed |