Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170478 | 0.83 | ADRB2 (0.37) | FFAR1ACACBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6575889 | 0.74 | TAAR1 (0.43) | TAAR1CALM1MAOB | |
| SCHEMBL6851302 | 0.74 | SLC7A5 (0.39) | TAAR1POLBALDH1A1SLC7A5 | |
| SCHEMBL27876830 | 0.71 | KDM4E (0.53) | FFAR1ACACBKDM4ETAAR1MAOB | |
| SCHEMBL11338351 | 0.71 | TAAR1 (0.52) | ACACBTAAR1MAOB | |
| SCHEMBL28181025 | 0.71 | GPR88 (0.44) | ACACBPPARGPPARAALDH1A1 | |
| SCHEMBL13041414 | 0.70 | F2RL1 (0.59) | FFAR1KDM4ETAAR1POLBALDH1A1 | |
| SCHEMBL9036586 | 0.69 | HRH1 (0.47) | ACACBKDM4ETAAR1POLBALDH1A1 | |
| SCHEMBL15330172 | 0.69 | FFAR1 (0.56) | FFAR1ACACBKDM4EPOLBALDH1A1 | |
| SCHEMBL27483798 | 0.69 | TSHR (0.46) | ACACBPPARGPPARAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015535-A1 | SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES | Genzyme Corporation (US) | 2022-06-22 | — | — | EP | disclosed |