Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521645 | 0.83 | FFAR1 (0.38) | ACACBALDH1A1KDM4EFFAR1 | |
| SCHEMBL26741729 | 0.74 | SIGMAR1 (0.49) | ADRB2ACACBALDH1A1SIGMAR1KDM4E | |
| SCHEMBL23011590 | 0.74 | RAB9A (0.38) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL29342459 | 0.70 | SIGMAR1 (0.66) | ADRB2ALDH1A1SIGMAR1ADRB1HTT | |
| SCHEMBL10815976 | 0.68 | SIGMAR1 (0.60) | ALDH1A1SIGMAR1HTTSMN1; SMN2 | |
| SCHEMBL28181025 | 0.68 | GPR88 (0.44) | ACACBALDH1A1SIGMAR1 | |
| SCHEMBL16075057 | 0.68 | ACACB (0.52) | ACACBALDH1A1SIGMAR1KDM4EHTT | |
| SCHEMBL11550278 | 0.68 | ACACB (0.60) | ACACBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13041414 | 0.67 | F2RL1 (0.59) | ALDH1A1KDM4ESMN1; SMN2FFAR1 | |
| SCHEMBL25855169 | 0.67 | RXFP1 (0.49) | ALDH1A1KDM4ESMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895513-B1 | FC CONTAINING POLYPEPTIDES WITH ALTERED GLYCOSYLATION AND REDUCED EFFECTOR FUNCTION | GENZYME CORP (US) | 2018-05-23 | — | — | EP | disclosed |