Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431045 | 0.85 | — | — | |
| SCHEMBL17468422 | 0.82 | FAAH (0.36) | TDP1FAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL19703878 | 0.82 | FAAH (0.62) | FAAHMEN1KMT2ANAAA | |
| SCHEMBL30503483 | 0.80 | ITGB3 (0.43) | FAAHMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23584015 | 0.80 | FAAH (0.66) | FAAHMEN1KMT2ANAAA | |
| SCHEMBL13068427 | 0.80 | FAAH (0.66) | FAAHMEN1KMT2ANAAA | |
| SCHEMBL13663182 | 0.79 | FAAH (0.55) | FAAHMEN1KMT2ANAAAACHE | |
| SCHEMBL19704163 | 0.77 | FAAH (0.41) | TDP1FAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL20034810 | 0.77 | FAAH (0.41) | FAAHMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19466237 | 0.77 | TDP1 (0.36) | TDP1FAAHMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015535-A1 | SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES | Genzyme Corporation (US) | 2022-06-22 | — | — | EP | disclosed |