Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18942765 | 0.80 | MGLL (0.53) | HDAC1HDAC7FAAHMGLLPTGS1 | |
| SCHEMBL19886759 | 0.73 | MGLL (0.46) | FAAHMGLLPTGS1PTGS2ALDH1A1 | |
| SCHEMBL15304133 | 0.70 | ALDH1A1 (0.46) | ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL9617324 | 0.70 | GSR (0.48) | — | |
| SCHEMBL22381010 | 0.70 | GSR (0.48) | — | |
| SCHEMBL22687997 | 0.66 | MGLL (0.55) | FAAHMGLLPTGS1PTGS2ALDH1A1 | |
| SCHEMBL14679245 | 0.66 | MGLL (0.55) | FAAHMGLLPTGS1PTGS2ALDH1A1 | |
| SCHEMBL13646042 | 0.65 | OPRM1 (0.36) | FAAHMGLLPTGS1PTGS2TP53 | |
| SCHEMBL13647132 | 0.65 | OPRM1 (0.36) | FAAHMGLLPTGS1PTGS2TP53 | |
| SCHEMBL14136363 | 0.65 | ALDH1A1 (0.46) | MGLLELANEALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383846-B1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | OTAGO INNOVATION LTD (NZ) | 2022-06-22 | — | — | EP | disclosed |