Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.57 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.51 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521828 | 0.98 | ITGAV (0.60) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20153461 | 0.92 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20153349 | 0.92 | ITGAV (0.64) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20153385 | 0.92 | ITGAV (0.64) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20153378 | 0.90 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL24521903 | 0.90 | ITGAV (0.61) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL20153412 | 0.88 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL24521880 | 0.84 | SUCNR1 (0.38) | ITGAVITGB3ITGB6 | |
| SCHEMBL23558899 | 0.83 | ITGAV (0.58) | ITGAVITGB3ITGB6ITGB1ITGA5 | |
| SCHEMBL24521913 | 0.83 | ITGB3 (0.63) | ITGAVITGB3ITGB6ITGB8ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |