Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 14/20 | 0.38 |
| ▸ | OXGR1 | Q96P68 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.37 |
| ▸ | ITGAV | P06756 | 6/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153460 | 0.91 | SUCNR1 (0.39) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL20153379 | 0.88 | ITGB3 (0.33) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL20153358 | 0.86 | ITGB3 (0.33) | ITGB3ITGAV | |
| SCHEMBL24521878 | 0.84 | ITGAV (0.57) | ITGB3ITGAVITGB6 | |
| SCHEMBL24521828 | 0.82 | ITGAV (0.60) | ITGB3ITGAVITGB6 | |
| SCHEMBL21311584 | 0.78 | ITGB3 (0.38) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL20153461 | 0.77 | ITGAV (0.59) | ITGB3ITGAVITGB6 | |
| SCHEMBL20153349 | 0.74 | ITGAV (0.64) | ITGB3ITGAVITGB6 | |
| SCHEMBL20153385 | 0.74 | ITGAV (0.64) | ITGB3ITGAVITGB6 | |
| SCHEMBL24521903 | 0.74 | ITGAV (0.61) | ITGB3ITGAVITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |