Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 19/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 10/20 | 0.47 |
| ▸ | ITGB8 | P26012 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153412 | 0.85 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521902 | 0.84 | ITGB3 (0.61) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521881 | 0.77 | ITGB3 (0.56) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL29860487 | 0.76 | ITGAV (0.56) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL20153410 | 0.76 | ITGAV (0.52) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL20153336 | 0.75 | ITGB3 (0.64) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL20153505 | 0.74 | ITGB3 (0.53) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521899 | 0.73 | ITGB3 (0.67) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521878 | 0.73 | ITGAV (0.57) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL20153504 | 0.72 | ITGB3 (0.62) | ITGAVITGB3ITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |