Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075078 | 1.00 | TSHR (0.50) | TSHRPOLBACACBALDH1A1RAB9A | |
| SCHEMBL20850491 | 0.88 | LDHA (0.54) | TSHRACACBALDH1A1 | |
| SCHEMBL12733139 | 0.87 | POLB (0.51) | TSHRPOLBACACBALDH1A1RAB9A | |
| SCHEMBL16075073 | 0.87 | POLB (0.51) | POLBACACBRAB9AKDM4ENPC1 | |
| SCHEMBL20862302 | 0.87 | POLB (0.51) | POLBACACBRAB9AKDM4ENPC1 | |
| SCHEMBL24729011 | 0.87 | POLB (0.55) | POLBACACBALDH1A1RAB9AKDM4E | |
| SCHEMBL16075050 | 0.87 | POLB (0.51) | POLBACACBRAB9AKDM4ENPC1 | |
| SCHEMBL18588870 | 0.86 | TSHR (0.61) | TSHRPOLBALDH1A1RAB9ATHRB | |
| SCHEMBL19546006 | 0.85 | POLB (0.50) | POLBACACBALDH1A1RAB9AKDM4E | |
| SCHEMBL23967529 | 0.85 | TSHR (0.50) | TSHRPOLBACACBALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015518-B1 | ACTIVE-TARGETING NEAR-INFRARED FLUORESCENT MOLECULE FOR TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREFOR | NANJING NUOYUAN MEDICAL DEVICES CO LTD (CN) | 2023-10-25 | — | — | EP | disclosed |
| US-11718625-B2 | Near-infrared fluorescent molecule active targeting folate receptor and preparation method thereof | NANJING UOYUAN MEDICAL DEVICES CO., LTD (CN) | 2023-08-08 | — | — | US | disclosed |
| US-11718625-B2 | Near-infrared fluorescent molecule active targeting folate receptor and preparation method thereof | NANJING UOYUAN MEDICAL DEVICES CO., LTD (CN) | 2023-08-08 | — | — | US | disclosed |
| US-20220267330-A1 | NEAR-INFRARED FLUORESCENT MOLECULE ACTIVE TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREOF | NANJING NUOYUAN MEDICAL DEVICES CO., LTD (CN) | 2022-08-25 | — | — | US | disclosed |
| EP-4015518-A1 | ACTIVE-TARGETING NEAR-INFRARED FLUORESCENT MOLECULE FOR TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREFOR | Nanjing Nuoyuan Medical Devices Co., Ltd (CN) | 2022-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718625-B2 | Near-infrared fluorescent molecule active targeting folate receptor and preparation method thereof | FOLR1, FOLR2, DHFR | TSHR 1150/4885POLB 300/4885ACACB 4826/4885 |
| US-20220267330-A1 | NEAR-INFRARED FLUORESCENT MOLECULE ACTIVE TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREOF | FOLR1, FOLR2, DHFR | TSHR 1150/4885POLB 300/4885ACACB 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.