Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 7/20 | 0.32 |
| ▸ | CDK2 | P24941 | 4/20 | 0.32 |
| ▸ | BRD1 | O95696 | 2/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523721 | 0.85 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL24523802 | 0.82 | DPP4 (0.39) | ALDH1A1 | |
| SCHEMBL24601626 | 0.81 | ENPP3 (0.35) | CHEK1ALDH1A1ENPP3 | |
| SCHEMBL24523847 | 0.80 | CA1 (0.40) | ALDH1A1ENPP3L3MBTL1 | |
| SCHEMBL24601758 | 0.80 | CA1 (0.40) | ALDH1A1ENPP3L3MBTL1 | |
| SCHEMBL24523741 | 0.78 | ALDH1A1 (0.41) | CHEK1ALDH1A1CYP2A6ENPP3RXFP1 | |
| SCHEMBL24523819 | 0.78 | ENPP3 (0.35) | CHEK1ENPP3CDC7CDK2BRD4 | |
| SCHEMBL24523812 | 0.78 | MAPK10 (0.34) | ENPP3 | |
| SCHEMBL20821418 | 0.76 | PTGER4 (0.41) | CHEK1ALDH1A1ENPP3 | |
| SCHEMBL24523811 | 0.75 | ENPP3 (0.36) | CHEK1ALDH1A1CYP2A6ENPP3CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |