Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 2/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523749 | 0.88 | ENPP3 (0.39) | ENPP3G6PDCA1CA2 | |
| SCHEMBL24523811 | 0.87 | ENPP3 (0.36) | ENPP3CHEK1G6PDCA1CA2 | |
| SCHEMBL24523806 | 0.86 | ENPP3 (0.32) | ENPP3 | |
| SCHEMBL24523767 | 0.84 | CA1 (0.46) | ENPP3CA1CA2CDC7CDK2 | |
| SCHEMBL24524316 | 0.83 | KMO (0.33) | ENPP3 | |
| SCHEMBL24523815 | 0.82 | G6PD (0.39) | ENPP3G6PDCA1CA2 | |
| SCHEMBL24523831 | 0.82 | ENPP3 (0.37) | ENPP3CHEK1G6PDCA1CA2 | |
| SCHEMBL24523741 | 0.79 | ALDH1A1 (0.41) | ENPP3CHEK1G6PD | |
| SCHEMBL24601626 | 0.79 | ENPP3 (0.35) | ENPP3CHEK1G6PDCA1CA2 | |
| SCHEMBL24523732 | 0.78 | CHEK1 (0.36) | ENPP3CHEK1BRD4CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |