Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523765 | 0.91 | PTGDR2 (0.40) | MEN1KMT2APTGDR2CYP19A1METAP2 | |
| SCHEMBL24523822 | 0.87 | CA1 (0.41) | MEN1KMT2APTGDR2CYP19A1METAP2 | |
| SCHEMBL24523719 | 0.86 | MEN1 (0.39) | MEN1KMT2APTGDR2CYP19A1FASN | |
| SCHEMBL24523722 | 0.85 | MEN1 (0.38) | MEN1KMT2APTGDR2CYP19A1FASN | |
| SCHEMBL24523804 | 0.85 | GABRA1 (0.39) | MEN1KMT2ACYP19A1FASNENPP3 | |
| SCHEMBL24523724 | 0.85 | GABRA1 (0.39) | MEN1KMT2ACYP19A1FASNENPP3 | |
| SCHEMBL24523830 | 0.82 | ENPP3 (0.37) | PTGDR2CYP19A1ADORA2AADRA2CENPP3 | |
| SCHEMBL24523808 | 0.82 | CA1 (0.42) | ENPP3 | |
| SCHEMBL24523831 | 0.81 | ENPP3 (0.37) | MEN1KMT2AENPP3 | |
| SCHEMBL24523743 | 0.81 | RXFP1 (0.37) | DPP4ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |