Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NRP1 | O14786 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523831 | 0.83 | ENPP3 (0.37) | CHEK1ENPP3CDC7CDK2 | |
| SCHEMBL24523736 | 0.83 | DPP4 (0.35) | RXFP1CHEK1DPP4ENPP3 | |
| SCHEMBL24523734 | 0.81 | MEN1 (0.40) | DPP4ENPP3 | |
| SCHEMBL24523741 | 0.81 | ALDH1A1 (0.41) | RXFP1CHEK1ARENPP3ALDH1A1 | |
| SCHEMBL24523719 | 0.80 | MEN1 (0.39) | DPP4ENPP3 | |
| SCHEMBL24523801 | 0.80 | EGLN2 (0.34) | RXFP1CHEK1ARDPP4LCK | |
| SCHEMBL21710573 | 0.79 | PTGER4 (0.36) | RXFP1ENPP3ALDH1A1 | |
| SCHEMBL24523722 | 0.78 | MEN1 (0.38) | DPP4ENPP3 | |
| SCHEMBL24523724 | 0.78 | GABRA1 (0.39) | CHEK1ENPP3 | |
| SCHEMBL24523804 | 0.78 | GABRA1 (0.39) | CHEK1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |